KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRN
All Species:
21.52
Human Site:
Y628
Identified Species:
43.03
UniProt:
Q16849
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16849
NP_002837.1
979
105848
Y628
H
G
D
T
T
F
E
Y
Q
D
L
C
R
Q
H
Chimpanzee
Pan troglodytes
XP_516107
1019
110215
Y628
H
G
D
T
T
F
E
Y
Q
D
L
C
R
Q
H
Rhesus Macaque
Macaca mulatta
XP_001083323
498
55666
S171
R
P
E
G
P
H
T
S
R
I
S
S
V
S
S
Dog
Lupus familis
XP_536080
1066
115628
Y725
H
G
D
T
T
F
E
Y
Q
D
L
C
R
Q
H
Cat
Felis silvestris
Mouse
Mus musculus
Q60673
979
106069
Y628
H
G
D
T
T
F
E
Y
Q
D
L
C
R
Q
H
Rat
Rattus norvegicus
Q63259
983
106209
Y632
H
G
D
T
T
F
E
Y
Q
D
L
C
R
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511936
1140
127143
A789
D
P
S
S
D
A
T
A
A
Y
Q
E
L
C
R
Chicken
Gallus gallus
XP_418552
1017
113861
A666
D
A
G
S
D
A
T
A
A
Y
Q
E
L
C
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4IFW2
1909
213435
H1342
S
V
S
E
L
A
D
H
I
E
R
L
K
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_722672
1306
145632
R866
Y
Q
E
L
C
R
A
R
M
A
G
K
A
G
G
Honey Bee
Apis mellifera
XP_623773
902
104556
Y541
D
P
E
A
S
K
D
Y
Q
D
L
C
R
A
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789889
533
59466
P205
M
A
T
K
S
D
K
P
E
P
L
T
R
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.6
34.6
82.8
N.A.
86.9
87.2
N.A.
40.5
41.4
N.A.
20.3
N.A.
29.1
33.4
N.A.
33.4
Protein Similarity:
100
93.2
42
85.6
N.A.
90.8
91.1
N.A.
54.2
55.8
N.A.
31
N.A.
42.2
47.4
N.A.
44
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
0
0
N.A.
0
N.A.
0
40
N.A.
13.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
33.3
N.A.
13.3
60
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
0
25
9
17
17
9
0
0
9
17
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
50
0
17
0
% C
% Asp:
25
0
42
0
17
9
17
0
0
50
0
0
0
0
0
% D
% Glu:
0
0
25
9
0
0
42
0
9
9
0
17
0
0
0
% E
% Phe:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
42
9
9
0
0
0
0
0
0
9
0
0
9
9
% G
% His:
42
0
0
0
0
9
0
9
0
0
0
0
0
0
42
% H
% Ile:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
9
0
9
9
0
0
0
0
9
9
0
0
% K
% Leu:
0
0
0
9
9
0
0
0
0
0
59
9
17
0
0
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
25
0
0
9
0
0
9
0
9
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
50
0
17
0
0
42
0
% Q
% Arg:
9
0
0
0
0
9
0
9
9
0
9
0
59
0
25
% R
% Ser:
9
0
17
17
17
0
0
9
0
0
9
9
0
9
17
% S
% Thr:
0
0
9
42
42
0
25
0
0
0
0
9
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
50
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _